Pysam is a Python package for reading, manipulating, and writing genomics data such as SAM/BAM/CRAM and VCF/BCF files. It's a lightweight wrapper of the HTSlib API, the same one that powers samtools, bcftools, and tabix.
pysam-developers/pysam has 910 GitHub stars. It gained -1 stars over 1 recorded day in the last 7 days (snapshots through Nov 3, 2026).
It currently ranks #9427 daily, #10576 weekly, #14311 monthly by momentum on Trending Repos; its best-ever rank is #8614.
Trending Repos first recorded it on May 22, 2026.
| Date | Stars gained | Total stars | Forks gained |
|---|---|---|---|
| -1 | 910 | +1 |